Abstract

Objectives: In this study, we evaluated vitamin D levels in the patients with early Parkinson’s disease based on the relationship between Parkinson’s disease and vitamin D deficiency.

Patients and Methods: Fifty consecutive patients with idiopathic Parkinson’s disease (25 females, 25 males; mean age 62.9±7.5 years) followed-up in our Parkinson outpatient clinic and 30 healthy volunteers (15 females, 15 males; mean age 62.1±6.1 years) were included into the study. All blood samples were obtained in July and August for possible seasonal differences. Vitamin D and vitamin D binding protein levels were studied by ELISA method. Statistical analysis was performed using Student’s t-test, Man-Whitney U-test, and Pearson’s correlation.

Results: The age and gender was similar between groups (p=0.59; p=0.82). The mean vitamin D level was 46.3±2.5 ng/ml in the patient group, while it was 46.3±23.9 ng/ml in the control group. There was no statistically significant difference between groups (p=0.99). Seven patients (14%) had vitamin D insufficiency, whereas seven patients (14%) had vitamin D deficiency in the patient group.

Conclusion: The existence of hypovitaminosis D either in the patient or control group may suggest a serious health problem.