Delayed neurological complication due to carbon monoxide intoxication: A case report of parkinsonism
Burcu Saadet Zeybek, Mehmet Balal
Çukurova Üniversitesi Tıp Fakültesi Nöroloji Anabilim Dalı, Adana, Türkiye
Keywords: Carbon monoxide intoxication, delayed neurological complication, dystonia, parkinsonism.
Abstract
Carbon monoxide (CO) intoxication is commonly encountered, particularly during the winter, and causes significant mortality and morbidity. The intoxication manifests with different clinical symptoms depending on the CO concentration in the environment, exposure time, and comorbid diseases. The presentation may vary from mild symptoms such as headaches, nausea, and vomiting to life-threatening conditions such as coma. Some delayed neurological complications may develop in the patients within several days to weeks after the acute phase is over. A 19-year-old male patient was admitted to our clinic with complaints of slowed movement, imbalance, and indifference to the environment starting five days after being exposed to generator gas. Neurological examination was consistent with parkinsonism and dystonia. Brain magnetic resonance imaging revealed bilateral symmetrical hyperintensities in the globulus pallidus consistent with hypoxia, supporting the diagnosis of parkinsonism. This case was presented to draw attention to the delayed neurological complications associated with CO intoxication.