Parkinson Hastalığı ve Hareket Bozuklukları Dergisi

Ahmet Mithat TAVLI,1 Nesrin HELVACI YILMAZ,1 Didem TAŞKIN,1 Lütfü HANOĞLU,1Yahya PAKSOY,2 Cem ERDOĞAN,3 Burcu HIZARCI,3 Mehmet Yücel AĞARGÜN4

1İstanbul Medipol Üniversitesi Tıp Fakültesi Nöroloji Anabilim Dalı, İstanbul, Türkiye
2İstanbul Medipol Üniversitesi Tıp Fakültesi Radyoloji Anabilim Dalı, İstanbul, Türkiye
3İstanbul Medipol Üniversitesi Tıp Fakültesi Anestezi ve Reanimasyon Anabilim Dalı, İstanbul, Türkiye
4İstanbul Medipol Üniversitesi Tıp Fakültesi Psikiyatri Anabilim Dalı, İstanbul, Türkiye

Keywords: Autoimmune encephalitis; basal ganglia; immunotherapy.

Abstract

In recent years, nonparaneoplastic autoimmune encephalitis has become one of the most studied topics after the identification of antibodies against surface specific antigens. In most patients, medial temporal lobe involvement is dominant, whereas basal ganglia are affected rarely. In this article, we report a 54-year-old female patient presenting with personality changes, dystonia, epileptic seizures, and caudate nucleus involvement on cranial magnetic resonance imaging, with no detected antibodies in cerebrospinal fluid; however, whose clinical findings improved with immunotherapy.