Abstract

Holmes’ tremor is a low frequency tremor which is diagnosed clinically, appears during rest, posture and action on especially proximal parts. It is generally associated with lesions (cerebrovascular diseases, trauma or multiple sclerosis) localized in midbrain or thalamus. Symptoms generally develop weeks, months and even years after the underlying cause. In this article, a case of Holmes’ tremor which developed approximately five months after the hemorrhage localized at upper part of midbrain secondary to cavernoma and the clinical and electrophysiological features, etiological factors and medical and surgical treatments of Holmes’ tremor is presented in the light of the literature.