Abstract

Although uncommon, the coexistence of Parkinson’s disease and bipolar disorder presents unique therapeutic challenges in both oral pharmacological treatments and the selection of device-aided interventions. Herein, we reported a 60-year-old male patient with both bipolar disorder and Parkinson’s disease. Apomorphine infusion therapy was initiated after motor symptoms remained uncontrolled despite optimized medical management. During a five-year follow-up, motor symptoms were effectively managed without any worsening of psychiatric status. Apomorphine infusion therapy may be considered a safe and effective treatment option for patients with advanced Parkinson’s disease and comorbid bipolar disorder.

Citation: Büyükkoyuncu Pekel N, Yıldız D. Balancing motor control and psychiatric stability: A five-year experience with apomorphine infusion in Parkinson’s disease and bipolar disorder. Parkinson Hast Harek Boz Derg 2025;28(1):9-12. doi: 10.5606/phhb.dergisi.2025.40.

Contributed to case management, manuscript drafting, and correspondence: N.B.P.; Contributed to literature review and critical revision. Both authors approved the final version of the manuscript: D.Y.

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

The authors received no financial support for the research and/or authorship of this article.

The data that support the findings of this study are available from the corresponding author upon reasonable request.