A case of Parkinson’s disease with clinical deterioration specific to constipation periods
Funda Kaplan1
, Zehra Yavuz2, Özlem Munis Bizpınar2, Selim Selçuk Çomoğlu2
1Ankara Sincan Eğitim ve Araştırma Hastanesi, Nöroloji Kliniği, Ankara, Türkiye
2Ankara Etlik Şehir Hastanesi, Nöroloji Kliniği, Ankara, Türkiye
Keywords: Constipation, levodopa, Parkinson’s disease.
Abstract
Parkinson’s disease is a neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons located in the substantia nigra pars compacta. It has a broad clinical spectrum, encompassing both motor and non-motor symptoms. Constipation is quite common within this clinical spectrum, accompanying the clinical picture in all stages of the disease. This case report presented a 62-year-old male patient whose motor symptoms worsened during periods of constipation and improved when the constipation resolved.