Journal of Parkinson's Disease and Movement Disorders

Nesibe Yıldız Akbulut, Banu Özen Barut

SBÜ Kartal Dr. Lütfi Kırdar Şehir Hastanesi, Nöroloji Kliniği, İstanbul, Türkiye

Keywords: Botulinum toxin, dental procedure, dystonia, oromandibulolingual.


Objectives: In this study, it was aimed to retrospectively examine the patients with oromandibulolingual dystonia followed up in our center and investigate related conditions.

Patients and Methods: The data of 20 oromandibulolingual dystonia patients (4 males, 16 females; mean age; 59.9±10.4 year; range, 38 to 77 year) who were followed up in our clinic were retrospectively evaluated between 01.01.2015 and 01.01.2022. Demographic characteristics, focal areas of involvement, classification, risk factors, etiological causes, treatment options, and treatment responses of the patients were analyzed.

Results: When classified according to focal areas of involvement, isolated lingual dystonia was found in eight (40%) patients, oromandibular dystonia was found in eight (40%), and oromandibular dystonia was accompanied by blepharospasm in four (20%). Secondary dystonia was detected in 13 (65%) patients. The most common secondary causes were a dental procedure in the last six months (30%, n=6) and antipsychotic drug use (25%, n=5). Botulinum toxin injection was applied to 17 (85%) patients, and 12 (70%) of these patients were satisfied with the treatment.

Conclusion: Different etiologies are responsible for oromandibulolingual dystonia, and primary idiopathic and secondary forms are present. Among secondary causes, the presence of a dental procedure in the last six months is proportionally remarkable. More detailed studies on the pathogenesis are needed. Botulinum toxin injection provides relief in most patients.