Parkinson Hastalığı ve Hareket Bozuklukları Dergisi

Ayhan ÖZTÜRK,1 Yıldız DEĞİRMENCİ,2 Fuat DEMİRCİ3

1Düzce Üniversitesi Tıp Fakültesi, Nöroloji Anabilim Dalı, Düzce, Türkiye
2Çanakkale Onsekiz Mart Üniversitesi Tıp Fakültesi, Nöroloji Anabilim Dalı, Çanakkale, Türkiye
3Düzce Üniversitesi Tıp Fakültesi, Obstetrik ve Jinekoloji Anabilim Dalı, Düzce, Türkiye

Keywords: Parkinson’s disease; quality of life index; urodynamia.

Abstract

Objectives: The aim of this study was to evaluate urodynamic findings in idiopathic Parkinson’s Disease (IPD) and to investigate the effects of these findings on the quality of life.

Patients and Methods: Twenty female patients (mean age 67.2±10.6 years; range 53 to 89 years) with idiopathic Parkinson’s disease and 20 healthy female volunteers (mean age 65±13.2 years; range 50 to 82 years) were included in this study. Severity of Parkinson’s disease was evaluated with Hoehn-Yahr staging. Quality of life was evaluated with “The Scales for Outcomes in Parkinson’s disease-Autonomic” (SCOPA-AUT) questionnaire including three subgroups (bladder, bowel and sexual function inquiry) in patient and control groups. Urodynamic evaluation was performed by multichannel cystometry device (MMS Dover, USA). Effects of urodynamic findings on quality of life was investigated in both groups.

Results: Higher rates of bladder and bowel dysfunction was detected in IPD group, when compared with the control group. Detrusor overactivity and hypocompliant bladder was significantly higher in IPD group (p<0.05). There was a positive correlation between Parkinson’s disease severity with frequency of detrusor overactivity and reduced quality of life index.

Conclusion: Since urodynamic findings which affect the quality of life badly, seen frequently in IPD, pelvic organ dysfunction treatment is considered among primary targets in the supportive therapy of Parkinson’s disease.