Journal of Parkinson's Disease and Movement Disorders

Çisil Çerçi Kubur1, Sibğatullah Ali Orak1, Muzaffer Polat2

1Department of Pediatric Neurology, Manisa Celal Bayar University Faculty of Medicine, Manisa, İzmir, Türkiye
2Department of Pediatrics, Manisa Celal Bayar University Faculty of Medicine, Manisa, İzmir, Türkiye

Keywords: Cerebellitis, COVID-19, immunotherapy, intravenous immunoglobulin.

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in Wuhan, China, in December 2019, has emerged as a major global public health threat. The literature on the severe neurological manifestations of coronavirus disease 2019 (COVID-19) has expanded substantially, with numerous studies and reviews documenting a wide spectrum of neurologic involvement. Nevertheless, COVID-19-associated cerebellitis in infants without accompanying systemic symptoms has not been previously described. Herein, we reported the case of a 12-month-old patient who presented with acute ataxia and was diagnosed with COVID-19-associated acute cerebellitis based on characteristic magnetic resonance imaging findings. The patient demonstrated notable clinical improvement following a five-day course of intravenous immunoglobulin. This case highlights the potential of SARS-CoV-2 to mimic diverse neurologic presentations, even in the absence of systemic manifestations, and underscores the importance of maintaining a high index of suspicion for COVID-19 in infants presenting with acute cerebellar dysfunction.

Citation: Çerçi Kubur Ç, Orak SA, Polat M. Acute cerebellitis in severe acute respiratory syndrome coronavirus 2 infection: A case report. Parkinson Hast Harek Boz Derg 2025;28(2-3):36-40.