Acute cerebellitis in SARS-CoV-2 infection: A case report
Çisil Çerçi Kubur1
, Sibğatullah Ali Orak1
, Muzaffer Polat2
1Department of Pediatric Neurology, Manisa Celal Bayar University Faculty of Medicine, Manisa, İzmir, Türkiye
2Department of Pediatrics, Manisa Celal Bayar University Faculty of Medicine, Manisa, İzmir, Türkiye
Keywords: Cerebellitis, COVID-19, immunotherapy, intravenous immunoglobulin.
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in Wuhan, China, in December 2019, has emerged as a major global public health threat. The literature on the severe neurological manifestations of coronavirus disease 2019 (COVID-19) has expanded substantially, with numerous studies and reviews documenting a wide spectrum of neurologic involvement. Nevertheless, COVID-19-associated cerebellitis in infants without accompanying systemic symptoms has not been previously described. Herein, we reported the case of a 12-month-old patient who presented with acute ataxia and was diagnosed with COVID-19-associated acute cerebellitis based on characteristic magnetic resonance imaging findings. The patient demonstrated notable clinical improvement following a five-day course of intravenous immunoglobulin. This case highlights the potential of SARS-CoV-2 to mimic diverse neurologic presentations, even in the absence of systemic manifestations, and underscores the importance of maintaining a high index of suspicion for COVID-19 in infants presenting with acute cerebellar dysfunction.
Citation: Çerçi Kubur Ç, Orak SA, Polat M. Acute cerebellitis in severe acute respiratory syndrome coronavirus 2 infection: A case report. Parkinson Hast Harek Boz Derg 2025;28(2-3):36-40.