Journal of Parkinson's Disease and Movement Disorders

Ayşegül GÜNDÜZ,1 Sabri AYDIN,2 Hülya APAYDIN,1 Güneş KIZILTAN,1 Sibel ERTAN,1Bashar ABUZAYED,2 Semra OĞUZ,3 Selin YAĞCI2

İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi, 1Nöroloji Anabilim Dalı, 2Nöroşirurji Anabilim Dalı,
3Fizik Tedavi ve Rehabilitasyon Anabilim Dalı, İstanbul, Türkiye

Keywords: Deep brain stimulation; dystonia; essential tremor; globus pallidus interna,; Parkinson’s disease; pedunculopontine nucleus; subthalamik nucleus; thalamic ventral intermediate nuclues.


Deep brain stimulation in movement disorders treatment is applied in cases of Parkinson’s disease resistant to medical treatment as well as in drug-resistant essential tremor and dystonia. Basis of this application is chronic electrical stimulation of certain nuclei by the way of electrode placed in the relevant nuclei. Currently, target nuclei include thalamic ventral intermediate nucleus, subthalamic nucleus, globus pallidus interna and more recently listed pedunculopontine nucleus although the target varies depending on the indication. Here, we aimed to review and summarize the indications, the benefits and risks as well as the patient selection criteria of deep brain stimulation in accepted fields of use among movement disorders.