Journal of Parkinson's Disease and Movement Disorders

Görkem Tutal Gürsoy, Fadime Erdoğan Küçükdağlı, İrem Sert, Tuğçe Saltoğlu, Yeşim Sücüllü Karadağ

Department of Neurology, Ankara City Hospital, Ankara, Turkey

Keywords: COVID-19, opsoclonus myoclonus, opsoclonus, SARS-CoV-2.


Opsoclonus is the irregular, arrhythmic, and chaotic eye movements in all directions of gaze, and it is frequently accompanied by ataxia, encephalopathy, and myoclonus. Accordingly, the term “opsoclonus-myoclonus syndrome” (OMS) has been introduced. Opsoclonus-myoclonus syndrome is a rare and heterogeneous neurological condition caused by infections, malignancies, toxic and metabolic disorders. Immune mechanisms are associated with OMS. Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the disease has many neurological manifestations. Opsoclonus-myoclonus syndrome can manifest in consequence of this infectious disease as a parainfectious condition. In this article, we report two cases of OMS developed after SARS-CoV-2 infection.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.